Treating diarrhoeal diseases with FXR agonists - Licensing Opportunity from Royal College of Surgeons in Ireland - July 2015 front page preview

Treating diarrhoeal diseases with FXR agonists - Licensing Opportunity from Royal College of Surgeons in Ireland - July 2015

The Farnesoid X receptor (FXR) is an important regulator of many physiological processes. There is currently a great deal of interest in therapeutically targeting FXR for a number of conditions, including liver disease, ...

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Single step encapsulation technology for drug formulation - Licensing Opportunity from Royal College of Surgeons in Ireland - July 2015 front page preview

Single step encapsulation technology for drug formulation - Licensing Opportunity from Royal College of Surgeons in Ireland - July 2015

RCSI Researchers have developed a single step micro-encapsulation process (MicroPET) for use in drug formulation to enable the delayed release, sustained release or targeted delivery of active pharmaceutical ingredients....

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Ground Breaking Discovery into the Causes of Amyotrophic Lateral Sclerosis (ALS) - Licensing Opportunity from Royal College of Surgeons in Ireland - July 2015 front page preview

Ground Breaking Discovery into the Causes of Amyotrophic Lateral Sclerosis (ALS) - Licensing Opportunity from Royal College of Surgeons in Ireland - July 2015

Amyotrophic lateral sclerosis (ALS) is the most common neurodegenerative disorder of young and middle aged adults that is incurable and invariably fatal. Novel disease‐ specific mutations in a particular gene have recen...

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Disease-modifying treatment for epilepsy - Licensing Opportunity from Royal College of Surgeons in Ireland - July 2015 front page preview

Disease-modifying treatment for epilepsy - Licensing Opportunity from Royal College of Surgeons in Ireland - July 2015

Researchers at RCSI have discovered that levels of microRNA-134 are abnormally high in human epilepsy and silencing microRNA-134 expression in vivo using a microRNA-134 antagomir (“miR134”) rendered mice refractory to bo...

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A topical gel formulation for accelerated healing of chronic wounds - Licensing Opportunity from Royal College of Surgeons in Ireland - July 2015 front page preview

A topical gel formulation for accelerated healing of chronic wounds - Licensing Opportunity from Royal College of Surgeons in Ireland - July 2015

Researchers at RCSI have developed a patented, topical gel formulation that releases an active agent (phenytoin) in a controlled manner to increase the rate of chronic wound healing. Data obtained in pre-clinical and som...

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